aja wrote:
I think the only way to change the actual tuning would be to get a MIDI guitar or one like the Variax
Pitch shifting is fairly complex at the best of times and can only shift the entire sound up or down - can't give you altered tunings, which I think is what you are after. If you want to tune individual strings differently, you need something that uses a hex pickup - Currently limited to the Line 6 Variax, Fender VG-Strat, or a guitar with a hex pickup and a Roland VG-99. None are inexpensive options.
The new version of the Celemony Melodyne software can take a prerecorded part and change it's key (pretty amazing piece of software - if only people would stop using it just for the Autotune type effect). It's not realtime though.
However - If you're looking to change tunings on the fly then there are hardware options too. The Hipshot Trilogy bridge (hardtail only) can swap the tunings of each string to any of three preset notes on the fly. There is also the Steinberger Trans-trem tremolo (headless guitars only) which can be preset to lock into different tunings (even while playing) and can also drop and raise the pitch of all the strings in tune with each other..